3zlf: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_3zlf|  PDB=3zlf  |  SCENE=  }}
===Structure of group A Streptococcal enolase K312A mutant===


The entry 3zlf is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>  


Authors: Cork, A.J., Ericsson, D.J., Law, R.H.P., Casey, L.W., Valkov, E., Bertozzi, C., Stamp, A., Aquilina, J.A., Whisstock, J.C., Walker, M.J., Kobe, B.
==About this Structure==
[[3zlf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA].  


Description: Structure of group A Streptococcal enolase K312A mutant
==Reference==
<references group="xtra"/><references/>
[[Category: Phosphopyruvate hydratase]]
[[Category: Aquilina, J A.]]
[[Category: Bertozzi, C.]]
[[Category: Casey, L W.]]
[[Category: Cork, A J.]]
[[Category: Ericsson, D J.]]
[[Category: Kobe, B.]]
[[Category: Law, R H.P.]]
[[Category: Stamp, A.]]
[[Category: Valkov, E.]]
[[Category: Walker, M J.]]
[[Category: Whisstock, J C.]]
[[Category: Lyase]]
[[Category: Plasminogen-binding]]

Revision as of 11:28, 5 February 2014

Template:STRUCTURE 3zlf

Structure of group A Streptococcal enolase K312A mutant

Function

[ENO_STRP6] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.[1]

About this Structure

3zlf is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Pancholi V, Fischetti VA. alpha-enolase, a novel strong plasmin(ogen) binding protein on the surface of pathogenic streptococci. J Biol Chem. 1998 Jun 5;273(23):14503-15. PMID:9603964

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