3lja: Difference between revisions
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{{STRUCTURE_3lja| PDB=3lja | SCENE= }} | {{STRUCTURE_3lja| PDB=3lja | SCENE= }} | ||
===Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome=== | ===Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome=== | ||
{{ABSTRACT_PUBMED_20350553}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H32_XENLA H32_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H4_XENLA H4_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | |||
==About this Structure== | ==About this Structure== | ||
[[3lja]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3lja]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJA OCA]. | ||
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:020350553</ref><references group="xtra"/> | <ref group="xtra">PMID:020350553</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: African clawed frog]] | ||
[[Category: Davey, C A.]] | [[Category: Davey, C A.]] | ||
[[Category: Wu, B.]] | [[Category: Wu, B.]] | ||