4lyk: Difference between revisions
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{{STRUCTURE_4lyk| PDB=4lyk | SCENE= }} | {{STRUCTURE_4lyk| PDB=4lyk | SCENE= }} | ||
===Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with activating cofactor Mg++=== | ===Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with activating cofactor Mg++=== | ||
{{ABSTRACT_PUBMED_24451384}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4lyk]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LYK OCA]. | [[4lyk]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LYK OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:024451384</ref><references group="xtra"/><references/> | |||
[[Category: Schirmer, T.]] | [[Category: Schirmer, T.]] | ||
[[Category: Sundriyal, A.]] | [[Category: Sundriyal, A.]] | ||
Revision as of 04:22, 13 February 2014
Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with activating cofactor Mg++
Template:ABSTRACT PUBMED 24451384
Function
[YAHA_ECOLI] Hydrolyzes c-di-GMP (cyclic bis(3'-5') dimeric GMP) to 5'-pGpG, known as PDE-A activity. PDE-B activity, that is hydrolysis of 5'-pGpG to GMP, proceeds only very slowly.
About this Structure
4lyk is a 4 chain structure. Full crystallographic information is available from OCA.
Reference
- Sundriyal A, Massa C, Samoray D, Zehender F, Sharpe T, Jenal U, Schirmer T. Inherent regulation of EAL domain-catalyzed hydrolysis of second messenger c-di-GMP. J Biol Chem. 2014 Jan 22. PMID:24451384 doi:https://dx.doi.org/10.1074/jbc.M113.516195