4kcp: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4kcp| PDB=4kcp | SCENE= }} | |||
===Structure of bovine endotheial nitric oxide synthase heme domain in complex with N-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide=== | |||
{{ABSTRACT_PUBMED_24447275}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/NOS3_BOVIN NOS3_BOVIN]] Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. | |||
==About this Structure== | |||
[[4kcp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KCP OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024447275</ref><references group="xtra"/><references/> | |||
[[Category: Chreifi, G.]] | |||
[[Category: Li, H.]] | |||
[[Category: Poulos, T L.]] | |||
[[Category: Nitric oxide synthase]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||