4cd3: Difference between revisions
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{{STRUCTURE_4cd3| PDB=4cd3 | SCENE= }} | |||
===RnNTPDase2 X4 variant in complex with PSB-071=== | |||
{{ABSTRACT_PUBMED_24462745}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ENTP2_RAT ENTP2_RAT]] In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. | |||
==About this Structure== | |||
[[4cd3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD3 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024462745</ref><references group="xtra"/><references/> | |||
[[Category: Schaefer, P.]] | |||
[[Category: Straeter, N.]] | |||
[[Category: Zebisch, M.]] | |||
[[Category: Apyrase]] | |||
[[Category: Atpase]] | |||
[[Category: Drug design]] | |||
[[Category: Hydrolase]] | |||
[[Category: Inhibitor]] | |||
[[Category: Ntpdase]] | |||
[[Category: Purinergic signalling]] | |||
Revision as of 05:10, 13 February 2014
RnNTPDase2 X4 variant in complex with PSB-071
Template:ABSTRACT PUBMED 24462745
Function
[ENTP2_RAT] In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent.
About this Structure
4cd3 is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Zebisch M, Baqi Y, Schafer P, Muller CE, Strater N. Crystal structure of NTPDase2 in complex with the sulfoanthraquinone inhibitor PSB-071. J Struct Biol. 2014 Jan 21. pii: S1047-8477(14)00006-9. doi:, 10.1016/j.jsb.2014.01.005. PMID:24462745 doi:https://dx.doi.org/10.1016/j.jsb.2014.01.005
