2mju: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_2mju|  PDB=2mju  |  SCENE=  }}
===Solution structure of a C terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB)===


The entry 2mju is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/PTBP2_HUMAN PTBP2_HUMAN]] RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. Beside its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.<ref>PMID:11003644</ref> <ref>PMID:12667457</ref> 


Authors: Esteve, V., Blatter, M., Allain, F.H.-T.
==About this Structure==
[[2mju]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJU OCA].  


Description: Solution structure of a C terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB)
==Reference==
<references group="xtra"/><references/>
[[Category: Allain, F H.T.]]
[[Category: Blatter, M.]]
[[Category: Esteve, V.]]
[[Category: Nptb]]
[[Category: Splicing]]