2ivi: Difference between revisions
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{{STRUCTURE_2ivi| PDB=2ivi | SCENE= }} | {{STRUCTURE_2ivi| PDB=2ivi | SCENE= }} | ||
=== | ===Isopenicillin N Synthase From Aspergillus Nidulans (Anaerobic Ac- methyl-cyclopropylglycine Fe Complex)=== | ||
{{ABSTRACT_PUBMED_17397141}} | {{ABSTRACT_PUBMED_17397141}} | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/IPNS_EMENI IPNS_EMENI]] Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin. | |||
==About this Structure== | ==About this Structure== | ||
[[2ivi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[2ivi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/A._nidulans A. nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVI OCA]. | ||
==See Also== | ==See Also== | ||
| Line 10: | Line 13: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:017397141</ref>< | <ref group="xtra">PMID:017397141</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: A. nidulans]] | ||
[[Category: Isopenicillin-N synthase]] | [[Category: Isopenicillin-N synthase]] | ||
[[Category: Adlington, R M.]] | [[Category: Adlington, R M.]] | ||
Revision as of 14:18, 19 February 2014
Isopenicillin N Synthase From Aspergillus Nidulans (Anaerobic Ac- methyl-cyclopropylglycine Fe Complex)
Template:ABSTRACT PUBMED 17397141
Function
[IPNS_EMENI] Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin.
About this Structure
2ivi is a 1 chain structure with sequence from A. nidulans. Full crystallographic information is available from OCA.
See Also
Reference
- Howard-Jones AR, Elkins JM, Clifton IJ, Roach PL, Adlington RM, Baldwin JE, Rutledge PJ. Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight. Biochemistry. 2007 Apr 24;46(16):4755-62. Epub 2007 Mar 31. PMID:17397141 doi:10.1021/bi062314q
