3cbh: Difference between revisions
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New page: left|200px<br /><applet load="3cbh" size="450" color="white" frame="true" align="right" spinBox="true" caption="3cbh, resolution 2.0Å" /> '''THREE-DIMENSIONAL STR... |
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[[Image:3cbh.jpg|left|200px]]<br /><applet load="3cbh" size=" | [[Image:3cbh.jpg|left|200px]]<br /><applet load="3cbh" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="3cbh, resolution 2.0Å" /> | caption="3cbh, resolution 2.0Å" /> | ||
'''THREE-DIMENSIONAL STRUCTURE OF CELLOBIOHYDROLASE FROM TRICHODERMA REESEI'''<br /> | '''THREE-DIMENSIONAL STRUCTURE OF CELLOBIOHYDROLASE FROM TRICHODERMA REESEI'''<br /> | ||
==Overview== | ==Overview== | ||
The enzymatic degradation of cellulose is an important process, both | The enzymatic degradation of cellulose is an important process, both ecologically and commercially. The three-dimensional structure of a cellulase, the enzymatic core of CBHII from the fungus Trichoderma reesei reveals an alpha-beta protein with a fold similar to but different from the widely occurring barrel topology first observed in triose phosphate isomerase. The active site of CBHII is located at the carboxyl-terminal end of a parallel beta barrel, in an enclosed tunnel through which the cellulose threads. Two aspartic acid residues, located in the center of the tunnel are the probable catalytic residues. | ||
==About this Structure== | ==About this Structure== | ||
3CBH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Hypocrea_jecorina Hypocrea jecorina]. Active as [http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase Cellulose 1,4-beta-cellobiosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] Full crystallographic information is available from [http:// | 3CBH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Hypocrea_jecorina Hypocrea jecorina]. Active as [http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase Cellulose 1,4-beta-cellobiosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CBH OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Hypocrea jecorina]] | [[Category: Hypocrea jecorina]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Jones, T | [[Category: Jones, T A.]] | ||
[[Category: Rouvinen, J.]] | [[Category: Rouvinen, J.]] | ||
[[Category: hydrolase (o-glycosyl)]] | [[Category: hydrolase (o-glycosyl)]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:08:42 2008'' | ||
