3zif: Difference between revisions

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{{Large structure}}
{{STRUCTURE_3zif|  PDB=3zif  |  SCENE=  }}  
{{STRUCTURE_3zif|  PDB=3zif  |  SCENE=  }}  
===Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly===
===Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly===
{{ABSTRACT_PUBMED_24503080}}


==Function==
==Function==
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==About this Structure==
==About this Structure==
[[3zif]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovine_adenovirus_3 Bovine adenovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZIF OCA].  
[[3zif]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovine_adenovirus_3 Bovine adenovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZIF OCA].  
==Reference==
<ref group="xtra">PMID:024503080</ref><references group="xtra"/><references/>
[[Category: Bovine adenovirus 3]]
[[Category: Bovine adenovirus 3]]
[[Category: Cheng, L.]]
[[Category: Cheng, L.]]

Revision as of 15:15, 19 February 2014

Warning: this is a large structure, and loading might take a long time or not happen at all.

Template:STRUCTURE 3zif

Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly

Template:ABSTRACT PUBMED 24503080

Function

[CAPSH_ADEB3] Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus (By similarity).

About this Structure

3zif is a 18 chain structure with sequence from Bovine adenovirus 3. Full crystallographic information is available from OCA.

Reference

  1. Cheng L, Huang X, Li X, Xiong W, Sun W, Yang C, Zhang K, Wang Y, Liu H, Huang X, Ji G, Sun F, Zheng C, Zhu P. Cryo-EM structures of two bovine adenovirus type 3 intermediates. Virology. 2014 Feb;450-451:174-81. doi: 10.1016/j.virol.2013.12.012. Epub 2014, Jan 3. PMID:24503080 doi:https://dx.doi.org/10.1016/j.virol.2013.12.012

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