3gbp: Difference between revisions

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[[Image:3gbp.gif|left|200px]]<br /><applet load="3gbp" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:3gbp.gif|left|200px]]<br /><applet load="3gbp" size="350" color="white" frame="true" align="right" spinBox="true"

caption="3gbp, resolution 2.4Å" />

'''STRUCTURE OF THE PERIPLASMIC GLUCOSE/GALACTOSE RECEPTOR OF SALMONELLA TYPHIMURIUM'''<br />

==Overview==

The X-ray structure of the periplasmic glucose/galactose receptor (binding, protein) of Salmonella typhimurium has been solved by the method of, multiple isomorphous replacement and refined to a resolution of 2.4 A with, an R-factor of 15.8%. The protein consists of two highly-similar, structural domains with a bound sugar molecule trapped between. A combined, sequence/structural approach is used to compare the structure of this, protein to a similar arabinose receptor. The new sequence alignment, obtained is used to analyze a number of features conserved for structural, and functional reasons. This information allowed the prediction of similar, features within the sequence of the analogous ribose receptor. Some of the, consequences of the structures for chemotaxis and transport are discussed.

The X-ray structure of the periplasmic glucose/galactose receptor (binding protein) of Salmonella typhimurium has been solved by the method of multiple isomorphous replacement and refined to a resolution of 2.4 A with an R-factor of 15.8%. The protein consists of two highly-similar structural domains with a bound sugar molecule trapped between. A combined sequence/structural approach is used to compare the structure of this protein to a similar arabinose receptor. The new sequence alignment obtained is used to analyze a number of features conserved for structural and functional reasons. This information allowed the prediction of similar features within the sequence of the analogous ribose receptor. Some of the consequences of the structures for chemotaxis and transport are discussed.

==About this Structure==

3GBP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with GLC and CA as [http://en.wikipedia.org/wiki/ligands ligands]. This structure ~~superseeds~~ the now removed PDB entry 1GBP. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=3GBP OCA].

3GBP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=GLC:'>GLC</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 1GBP. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBP OCA].

==Reference==

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[[Category: Salmonella typhimurium]]

[[Category: Single protein]]

[[Category: Mowbray, S.L.]]

[[Category: Mowbray, S L.]]

[[Category: CA]]

[[Category: GLC]]

[[Category: periplasmic binding protein]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Tue Nov 20~~ 19:44:~~14 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:09:27 2008''

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@@ Line 1: / Line 1: @@
-[[Image:3gbp.gif|left|200px]]<br /><applet load="3gbp" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:3gbp.gif|left|200px]]<br /><applet load="3gbp" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="3gbp, resolution 2.4&Aring;" />
 '''STRUCTURE OF THE PERIPLASMIC GLUCOSE/GALACTOSE RECEPTOR OF SALMONELLA TYPHIMURIUM'''<br />
 ==Overview==
-The X-ray structure of the periplasmic glucose/galactose receptor (binding, protein) of Salmonella typhimurium has been solved by the method of, multiple isomorphous replacement and refined to a resolution of 2.4 A with, an R-factor of 15.8%. The protein consists of two highly-similar, structural domains with a bound sugar molecule trapped between. A combined, sequence/structural approach is used to compare the structure of this, protein to a similar arabinose receptor. The new sequence alignment, obtained is used to analyze a number of features conserved for structural, and functional reasons. This information allowed the prediction of similar, features within the sequence of the analogous ribose receptor. Some of the, consequences of the structures for chemotaxis and transport are discussed.
+The X-ray structure of the periplasmic glucose/galactose receptor (binding protein) of Salmonella typhimurium has been solved by the method of multiple isomorphous replacement and refined to a resolution of 2.4 A with an R-factor of 15.8%. The protein consists of two highly-similar structural domains with a bound sugar molecule trapped between. A combined sequence/structural approach is used to compare the structure of this protein to a similar arabinose receptor. The new sequence alignment obtained is used to analyze a number of features conserved for structural and functional reasons. This information allowed the prediction of similar features within the sequence of the analogous ribose receptor. Some of the consequences of the structures for chemotaxis and transport are discussed.
 ==About this Structure==
-GBP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with GLC and CA as [http://en.wikipedia.org/wiki/ligands ligands]. This structure superseeds the now removed PDB entry 1GBP. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=3GBP OCA].
+GBP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=GLC:'>GLC</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 1GBP. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBP OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Salmonella typhimurium]]
 [[Category: Single protein]]
-[[Category: Mowbray, S.L.]]
+[[Category: Mowbray, S L.]]
 [[Category: CA]]
 [[Category: GLC]]
 [[Category: periplasmic binding protein]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 19:44:14 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:09:27 2008''