4ofd: Difference between revisions
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{{STRUCTURE_4ofd| PDB=4ofd | SCENE= }} | |||
===Crystal Structure of mouse Neph1 D1-D2=== | |||
{{ABSTRACT_PUBMED_24485456}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KIRR1_MOUSE KIRR1_MOUSE]] Plays a significant role in the normal development and function of the glomerular permeability. Is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.<ref>PMID:11416156</ref> | |||
==About this Structure== | |||
[[4ofd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFD OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024485456</ref><references group="xtra"/><references/> | |||
[[Category: Garcia, K C.]] | |||
[[Category: Ozkan, E.]] | |||
[[Category: Blood filtration]] | |||
[[Category: Cell adhesion]] | |||
[[Category: Extracellular]] | |||
[[Category: Immunoglobulin superfamily]] | |||
[[Category: Kidney]] | |||
[[Category: Membrane]] | |||
[[Category: N-linked glycosylation]] | |||
[[Category: Protein binding]] | |||
[[Category: Signaling protein]] | |||
Revision as of 17:29, 19 February 2014
Crystal Structure of mouse Neph1 D1-D2
Template:ABSTRACT PUBMED 24485456
Function
[KIRR1_MOUSE] Plays a significant role in the normal development and function of the glomerular permeability. Is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.[1]
About this Structure
4ofd is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Ozkan E, Chia PH, Wang RR, Goriatcheva N, Borek D, Otwinowski Z, Walz T, Shen K, Garcia KC. Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis. Cell. 2014 Jan 30;156(3):482-94. doi: 10.1016/j.cell.2014.01.004. PMID:24485456 doi:https://dx.doi.org/10.1016/j.cell.2014.01.004
- ↑ Donoviel DB, Freed DD, Vogel H, Potter DG, Hawkins E, Barrish JP, Mathur BN, Turner CA, Geske R, Montgomery CA, Starbuck M, Brandt M, Gupta A, Ramirez-Solis R, Zambrowicz BP, Powell DR. Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN. Mol Cell Biol. 2001 Jul;21(14):4829-36. PMID:11416156 doi:https://dx.doi.org/10.1128/MCB.21.14.4829-4836.2001
