4kt8: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4kt8|  PDB=4kt8  |  SCENE=  }}
===The complex structure of Rv3378c-Y51FY90F with substrate, TPP===
{{ABSTRACT_PUBMED_24475925}}


The entry 4kt8 is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/TUBOL_MYCTU TUBOL_MYCTU]] Catalyzes the PP-removal from tuberculosinyl diphosphate to produce both tubercilosinol and isotuberculosinol. Can also use labdadienyl diphosphates, copalyl diphosphate (CDP), ent-CDP and syn-CDP in vitro.


Authors: Chan, H.C., Ko, T.P., Feng, X., Liu, W., Zheng, Y., Huang, C.H., Hu, Y., Bogue, S., Nakkno, C., Hoshino, T., Zhang, L., Lv, P., Cui, Y., Li, J., Liang, P.H., Wang, H.-J., Oldfield, E., Guo, R.T.
==About this Structure==
[[4kt8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KT8 OCA].  


Description: The complex structure of Rv3378c-Y51FY90F with substrate, TPP
==Reference==
<ref group="xtra">PMID:024475925</ref><references group="xtra"/><references/>
[[Category: Bogue, S.]]
[[Category: Chan, H C.]]
[[Category: Crick, D C.]]
[[Category: Feng, X.]]
[[Category: Guo, R T.]]
[[Category: Hoshino, T.]]
[[Category: Hu, Y.]]
[[Category: Huang, C H.]]
[[Category: Ko, T P.]]
[[Category: Liang, P H.]]
[[Category: Liu, W.]]
[[Category: Lv, P.]]
[[Category: Nakano, C.]]
[[Category: Oldfield, E.]]
[[Category: Wang, A H.]]
[[Category: Zhang, L.]]
[[Category: Zheng, Y.]]
[[Category: Diterpene synthase]]
[[Category: Hydrolase]]

Revision as of 18:12, 3 March 2014

Template:STRUCTURE 4kt8

The complex structure of Rv3378c-Y51FY90F with substrate, TPP

Template:ABSTRACT PUBMED 24475925

Function

[TUBOL_MYCTU] Catalyzes the PP-removal from tuberculosinyl diphosphate to produce both tubercilosinol and isotuberculosinol. Can also use labdadienyl diphosphates, copalyl diphosphate (CDP), ent-CDP and syn-CDP in vitro.

About this Structure

4kt8 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Chan HC, Feng X, Ko TP, Huang CH, Hu Y, Zheng Y, Bogue S, Nakano C, Hoshino T, Zhang L, Lv P, Liu W, Crick DC, Liang PH, Wang AH, Oldfield E, Guo RT. Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis. J Am Chem Soc. 2014 Feb 5. PMID:24475925 doi:https://dx.doi.org/10.1021/ja413127v

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