4irb: Difference between revisions
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{{STRUCTURE_4irb| PDB=4irb | SCENE= }} | |||
===Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4=== | |||
{{ABSTRACT_PUBMED_23519808}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/UNG_VACCA UNG_VACCA]] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA. | |||
==About this Structure== | |||
[[4irb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRB OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023519808</ref><references group="xtra"/><references/> | |||
[[Category: Uracil-DNA glycosylase]] | |||
[[Category: Chattopadhyay, D.]] | |||
[[Category: Nuth, M.]] | |||
[[Category: Ricciardi, R P.]] | |||
[[Category: Sartmatova, D.]] | |||
[[Category: Schormann, N.]] | |||
[[Category: Zhukovskaya, N.]] | |||
[[Category: Beta- sheets at n- and c-terminus]] | |||
[[Category: Binding partners a20 and dna]] | |||
[[Category: Component of processivity factor]] | |||
[[Category: Dimeric assembly]] | |||
[[Category: Dna repair hydrolase]] | |||
[[Category: Hydrolase]] | |||
[[Category: Parallel beta-sheet of 4 strands in the order 2134]] | |||
[[Category: Viral protein]] | |||
Revision as of 18:15, 3 March 2014
Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4
Template:ABSTRACT PUBMED 23519808
Function
[UNG_VACCA] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA.
About this Structure
4irb is a 4 chain structure. Full crystallographic information is available from OCA.
Reference
- Sartmatova D, Nash T, Schormann N, Nuth M, Ricciardi R, Banerjee S, Chattopadhyay D. Crystallization and preliminary X-ray diffraction analysis of three recombinant mutants of Vaccinia virus uracil DNA glycosylase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69(Pt 3):295-301., doi: 10.1107/S1744309113002716. Epub 2013 Feb 23. PMID:23519808 doi:https://dx.doi.org/10.1107/S1744309113002716
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Uracil-DNA glycosylase
- Chattopadhyay, D.
- Nuth, M.
- Ricciardi, R P.
- Sartmatova, D.
- Schormann, N.
- Zhukovskaya, N.
- Beta- sheets at n- and c-terminus
- Binding partners a20 and dna
- Component of processivity factor
- Dimeric assembly
- Dna repair hydrolase
- Hydrolase
- Parallel beta-sheet of 4 strands in the order 2134
- Viral protein
