4mgt: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4mgt|  PDB=4mgt  |  SCENE=  }}
===ALKBH2 R110A cross-linked to undamaged dsDNA===


The entry 4mgt is ON HOLD until Aug 28 2015
==Function==
[[http://www.uniprot.org/uniprot/ALKB2_HUMAN ALKB2_HUMAN]] Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.<ref>PMID:12486230</ref> <ref>PMID:12594517</ref> <ref>PMID:16174769</ref> <ref>PMID:18519673</ref> <ref>PMID:18432238</ref>  


Authors: Chen, B., Gan, J., Yang, C.G.
==About this Structure==
[[4mgt]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MGT OCA].  


Description: ALKBH2 R110A cross-linked to undamaged dsDNA
==Reference==
<references group="xtra"/><references/>
[[Category: DNA oxidative demethylase]]
[[Category: Chen, B.]]
[[Category: Gan, J.]]
[[Category: Yang, C G.]]
[[Category: Oxidoreductase-dna complex]]
[[Category: Protein-dna complex]]