4nn2: Difference between revisions
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{{STRUCTURE_4nn2| PDB=4nn2 | SCENE= }} | |||
===Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6=== | |||
The entry | ==Disease== | ||
[[http://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN]] Borjeson-Forssman-Lehmann syndrome. The disease is caused by mutations affecting the gene represented in this entry. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN]] Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.<ref>PMID:23229552</ref> | |||
==About this Structure== | |||
[[4nn2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NN2 OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Li,F.]] | |||
[[Category: Liu, Z.]] | |||
[[Category: Mei,Y.]] | |||
[[Category: Shi,Y.]] | |||
[[Category: Wu, J.]] | |||
[[Category: Zhang, J.]] | |||
[[Category: Transcription]] | |||
[[Category: Zinc finger]] | |||
Revision as of 18:26, 3 March 2014
Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6
Disease
[PHF6_HUMAN] Borjeson-Forssman-Lehmann syndrome. The disease is caused by mutations affecting the gene represented in this entry.
Function
[PHF6_HUMAN] Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.[1]
About this Structure
4nn2 is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Wang J, Leung JW, Gong Z, Feng L, Shi X, Chen J. PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis. J Biol Chem. 2013 Feb 1;288(5):3174-83. doi: 10.1074/jbc.M112.414839. Epub 2012, Dec 10. PMID:23229552 doi:https://dx.doi.org/10.1074/jbc.M112.414839
