4oq6: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4oq6|  PDB=4oq6  |  SCENE=  }}
===Crystal Structure of Human MCL-1 Bound to Inhibitor 4-hydroxy-4'-propylbiphenyl-3-carboxylic acid===
{{ABSTRACT_PUBMED_24582986}}


The entry 4oq6 is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/MCL1_HUMAN MCL1_HUMAN]] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<ref>PMID:10766760</ref> 


Authors: Petros, A.M., Swann, S.L., Song, D., Swinger, K., Park, C., Zhang, H., Wendt, M.D., Kunzer, A.R., Souers, A.J., Sun, C.
==About this Structure==
[[4oq6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OQ6 OCA].  


Description:
==Reference==
<ref group="xtra">PMID:024582986</ref><references group="xtra"/><references/>
[[Category: Kunzer, A R.]]
[[Category: Park, C.]]
[[Category: Petros, A M.]]
[[Category: Song, D.]]
[[Category: Souers, A J.]]
[[Category: Sun, C.]]
[[Category: Swann, S L.]]
[[Category: Swinger, K.]]
[[Category: Wendt, M D.]]
[[Category: Zhang, H.]]
[[Category: Apoptosis-inhibitor complex]]