4nrl: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Structure of hemagglutinin with F95Y mutation of influenza virus B/Lee/40===

~~The entry 4nrl is ON HOLD until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/HEMA_INBLE HEMA_INBLE]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.

~~Authors~~: ~~Ni, F., Mbawuike, I~~.N.~~, Kondrashkina, E~~.~~, Wang, Q~~.

==About this Structure==

[[4nrl]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NRL OCA].

~~Description~~: ~~Structure of hemagglutinin with F95Y mutation of influenza virus B~~/~~Lee~~/40

==Reference==

[[Category: Kondrashkina, E.]]

[[Category: Mbawuike, I N.]]

[[Category: Ni, F.]]

[[Category: Wang, Q.]]

[[Category: Ha]]

[[Category: Viral protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4nrl|  PDB=4nrl  |  SCENE=  }}
+===Structure of hemagglutinin with F95Y mutation of influenza virus B/Lee/40===
+{{ABSTRACT_PUBMED_24503069}}
-The entry 4nrl is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/HEMA_INBLE HEMA_INBLE]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
-Authors: Ni, F., Mbawuike, I.N., Kondrashkina, E., Wang, Q.
+==About this Structure==
+[[4nrl]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NRL OCA].
-Description: Structure of hemagglutinin with F95Y mutation of influenza virus B/Lee/40
+==Reference==
+<ref group="xtra">PMID:024503069</ref><references group="xtra"/><references/>
+[[Category: Kondrashkina, E.]]
+[[Category: Mbawuike, I N.]]
+[[Category: Ni, F.]]
+[[Category: Wang, Q.]]
+[[Category: Ha]]
+[[Category: Viral protein]]