4ocm: Difference between revisions
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{{STRUCTURE_4ocm| PDB=4ocm | SCENE= }} | {{STRUCTURE_4ocm| PDB=4ocm | SCENE= }} | ||
===Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ib=== | ===Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ib=== | ||
{{ABSTRACT_PUBMED_24516147}} | |||
==Function== | ==Function== | ||
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==Reference== | ==Reference== | ||
<references group="xtra"/><references/> | <ref group="xtra">PMID:024516147</ref><references group="xtra"/><references/> | ||
[[Category: Bracher, A.]] | [[Category: Bracher, A.]] | ||
[[Category: Pathare, G R.]] | [[Category: Pathare, G R.]] | ||
Revision as of 09:07, 19 March 2014
Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ib
Template:ABSTRACT PUBMED 24516147
Function
[RPN8_YEAST] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.[1] [RPN11_YEAST] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.[2]
About this Structure
4ocm is a 6 chain structure. Full crystallographic information is available from OCA.
Reference
- Pathare GR, Nagy I, Sledz P, Anderson DJ, Zhou HJ, Pardon E, Steyaert J, Forster F, Bracher A, Baumeister W. Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):2984-9. doi:, 10.1073/pnas.1400546111. Epub 2014 Feb 10. PMID:24516147 doi:https://dx.doi.org/10.1073/pnas.1400546111
- ↑ Glickman MH, Rubin DM, Fried VA, Finley D. The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol. 1998 Jun;18(6):3149-62. PMID:9584156
- ↑ Chen L, Romero L, Chuang SM, Tournier V, Joshi KK, Lee JA, Kovvali G, Madura K. Sts1 plays a key role in targeting proteasomes to the nucleus. J Biol Chem. 2011 Jan 28;286(4):3104-18. doi: 10.1074/jbc.M110.135863. Epub 2010 , Nov 12. PMID:21075847 doi:10.1074/jbc.M110.135863
