3wp0: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===Crystal structure of Dlg GK in complex with a phosphor-Lgl2 peptide===

~~The entry 3wp0 is ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/DLG4_RAT DLG4_RAT]] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.<ref>PMID:15317815</ref> <ref>PMID:15358863</ref> [[http://www.uniprot.org/uniprot/L2GL2_HUMAN L2GL2_HUMAN]] Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.<ref>PMID:15632202</ref>

~~Authors~~: ~~Zhu, J., Shang,~~ .~~Y, Wan, Q~~.~~, Xia, Y~~.~~, Chen, J~~.~~, Du, Q, Zhang, M~~

==About this Structure==

[[3wp0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WP0 OCA].

~~Description~~: ~~Crystal structure of Dlg GK in complex with a phosphor-Lgl2 peptide~~

==Reference==

[[Category: Chen, J.]]

[[Category: Du, Q.]]

[[Category: Shang, Y.]]

[[Category: Wan, Q.]]

[[Category: Xia, Y.]]

[[Category: Zhang, M.]]

[[Category: Zhu, J.]]

[[Category: Cell polarity]]

[[Category: Maguk]]

[[Category: Peptide binding protein]]

[[Category: Phosphorylation]]

[[Category: Phosphorylation dependent]]

[[Category: Tumor suppressor]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_3wp0|  PDB=3wp0  |  SCENE=  }}
+===Crystal structure of Dlg GK in complex with a phosphor-Lgl2 peptide===
+{{ABSTRACT_PUBMED_24513855}}
-The entry 3wp0 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/DLG4_RAT DLG4_RAT]] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.<ref>PMID:15317815</ref> <ref>PMID:15358863</ref>  [[http://www.uniprot.org/uniprot/L2GL2_HUMAN L2GL2_HUMAN]] Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.<ref>PMID:15632202</ref>
-Authors: Zhu, J., Shang, .Y, Wan, Q., Xia, Y., Chen, J., Du, Q, Zhang, M
+==About this Structure==
+[[3wp0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WP0 OCA].
-Description: Crystal structure of Dlg GK in complex with a phosphor-Lgl2 peptide
+==Reference==
+<ref group="xtra">PMID:024513855</ref><references group="xtra"/><references/>
+[[Category: Chen, J.]]
+[[Category: Du, Q.]]
+[[Category: Shang, Y.]]
+[[Category: Wan, Q.]]
+[[Category: Xia, Y.]]
+[[Category: Zhang, M.]]
+[[Category: Zhu, J.]]
+[[Category: Cell polarity]]
+[[Category: Maguk]]
+[[Category: Peptide binding protein]]
+[[Category: Phosphorylation]]
+[[Category: Phosphorylation dependent]]
+[[Category: Tumor suppressor]]