4h5n: Difference between revisions
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{{STRUCTURE_4h5n| PDB=4h5n | SCENE= }} | |||
===HSC70 NBD with PO4, Na, Cl=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/HSP7C_HUMAN HSP7C_HUMAN]] Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.<ref>PMID:10722728</ref> | |||
==About this Structure== | |||
[[4h5n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H5N OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Stec, B.]] | |||
[[Category: Nucleotide binding domain]] | |||
[[Category: Transcription]] | |||