4clk: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4clk|  PDB=4clk  |  SCENE=  }}
===Crystal structure of human soluble Adenylyl Cyclase in complex with alpha,beta-methyleneadenosine-5'-triphosphate===
{{ABSTRACT_PUBMED_24567411}}


The entry 4clk is ON HOLD  until Paper Publication
==Disease==
[[http://www.uniprot.org/uniprot/ADCYA_HUMAN ADCYA_HUMAN]] Idiopathic hypercalciuria. Disease susceptibility is associated with variations affecting the gene represented in this entry.


Authors: Kleinboelting, S., Weyand, M., Steegborn, C.
==Function==
[[http://www.uniprot.org/uniprot/ADCYA_HUMAN ADCYA_HUMAN]] Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation.<ref>PMID:15659711</ref> <ref>PMID:17591988</ref> 


Description: Crystal structure of human soluble Adenylyl Cyclase in complex with alpha,beta-methyleneadenosine-5'-triphosphate
==About this Structure==
[[4clk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CLK OCA].
 
==Reference==
<ref group="xtra">PMID:024567411</ref><references group="xtra"/><references/>
[[Category: Adenylate cyclase]]
[[Category: Kleinboelting, S.]]
[[Category: Steegborn, C.]]
[[Category: Weyand, M.]]
[[Category: 5'-cyclic-monophosphate]]
[[Category: Adenosine-3'\]]
[[Category: Adenosine-5'-triphosphate]]
[[Category: Lyase]]
Retrieved from "https://proteopedia.org/4clk"