4ip8: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4ip8| PDB=4ip8 | SCENE= }} | |||
===Structure of human serum amyloid A1=== | |||
==Disease== | |||
[[http://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN]] Secondary amyloidosis. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN]] Major acute phase reactant. Apolipoprotein of the HDL complex. | |||
==About this Structure== | |||
[[4ip8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IP8 OCA]. | |||
[[Category: Lu, J.]] | |||
[[Category: Sun, P D]] | |||
[[Category: Four-helix bundle]] | |||
[[Category: Human serum]] | |||
[[Category: Main constituent of secondary amyloid]] | |||
[[Category: Protein binding]] | |||
[[Category: Secondary amyloid]] | |||
[[Category: Toll like receptor]] | |||
Revision as of 09:31, 26 March 2014
Structure of human serum amyloid A1
Disease
[SAA1_HUMAN] Secondary amyloidosis. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer.
Function
[SAA1_HUMAN] Major acute phase reactant. Apolipoprotein of the HDL complex.
About this Structure
4ip8 is a 4 chain structure. Full crystallographic information is available from OCA.
