4jts: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
Line 1: Line 1:
'''Unreleased structure'''
{{STRUCTURE_4jts|  PDB=4jts  |  SCENE=  }}
===Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 072===


The entry 4jts is ON HOLD until Paper Publication
==Disease==
[[http://www.uniprot.org/uniprot/PYRD_HUMAN PYRD_HUMAN]] Defects in DHODH are the cause of postaxial acrofacial dysostosis (POADS) [MIM:[http://omim.org/entry/263750 263750]]; also known as Miller syndrome. POADS is characterized by severe micrognathia, cleft lip and/or palate, hypoplasia or aplasia of the posterior elements of the limbs, coloboma of the eyelids and supernumerary nipples. POADS is a very rare disorder: only 2 multiplex families, each consisting of 2 affected siblings born to unaffected, nonconsanguineous parents, have been described among a total of around 30 reported cases.<ref>PMID:19915526</ref>  


Authors: Zhu, L.,, Zhu, J.,, Ren, X.,, Li, H.,
==Function==
[[http://www.uniprot.org/uniprot/PYRD_HUMAN PYRD_HUMAN]] Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.  


Description: Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 072
==About this Structure==
[[4jts]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JTS OCA].
 
==Reference==
<references group="xtra"/><references/>
[[Category: Li, H.]]
[[Category: Ren, X.]]
[[Category: Zhu, J.]]
[[Category: Zhu, L.]]
[[Category: Dhodh]]
[[Category: Fmn binding]]
[[Category: Mitochondria inner membrane]]
[[Category: Oxidoreductase]]
Retrieved from "https://proteopedia.org/4jts"