3qnl: Difference between revisions
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{{STRUCTURE_3qnl| PDB=3qnl | SCENE= }} | {{STRUCTURE_3qnl| PDB=3qnl | SCENE= }} | ||
===Crystal structure of PrTX-I complexed to Rosmarinic Acid=== | ===Crystal structure of PrTX-I complexed to Rosmarinic Acid=== | ||
{{ABSTRACT_PUBMED_22205953}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PA2H1_BOTPI PA2H1_BOTPI]] Snake venom phospholipase A2 (PLA2) homolog that lacks enzymatic activity, but displays myotoxin and edema-inducing activities in vivo. In vitro neuromuscular activities have also been observed, but they are not found in vivo and can be explained by the destabilization of the muscle membrane by the toxin. The myotoxic activity is inhibited by rosmarinic acid (RA).<ref>PMID:7660366</ref> <ref>PMID:22205953</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:022205953</ref><references group="xtra"/> | <ref group="xtra">PMID:022205953</ref><references group="xtra"/><references/> | ||
[[Category: Bothrops pirajai]] | [[Category: Bothrops pirajai]] | ||
[[Category: Fontes, M R.M.]] | [[Category: Fontes, M R.M.]] | ||
[[Category: Santos, J I.dos.]] | [[Category: Santos, J I.dos.]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||