4cjm: Difference between revisions
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{{STRUCTURE_4cjm| PDB=4cjm | SCENE= }} | |||
===Crystal structure of human FGF18=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FGF18_HUMAN FGF18_HUMAN]] Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.<ref>PMID:16597617</ref> | |||
==About this Structure== | |||
[[4cjm]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CJM OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024668462</ref><references group="xtra"/><references/> | |||
[[Category: Adam, L E.]] | |||
[[Category: Blundell, T L.]] | |||
[[Category: Brown, A.]] | |||
[[Category: Signaling protein]] | |||
[[Category: Signalling]] | |||
Revision as of 06:25, 9 April 2014
Crystal structure of human FGF18
Function
[FGF18_HUMAN] Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.[1]
About this Structure
4cjm is a 4 chain structure. Full crystallographic information is available from OCA.
Reference
- Brown A, Adam LE, Blundell TL. The crystal structure of fibroblast growth factor 18 (FGF18). Protein Cell. 2014 Mar 26. PMID:24668462 doi:https://dx.doi.org/10.1007/s13238-014-0033-4
- ↑ Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem. 2006 Jun 9;281(23):15694-700. Epub 2006 Apr 4. PMID:16597617 doi:10.1074/jbc.M601252200
