2mjn: Difference between revisions
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{{STRUCTURE_2mjn| PDB=2mjn | SCENE= }} | |||
===Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1=== | |||
{{ABSTRACT_PUBMED_24682828}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TIA1_HUMAN TIA1_HUMAN]] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. | |||
==About this Structure== | |||
[[2mjn]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJN OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024682828</ref><references group="xtra"/><references/> | |||
[[Category: Sattler, M.]] | |||
[[Category: Wang, I.]] | |||
[[Category: Rna binding protein]] | |||
[[Category: Rrm]] | |||
[[Category: Tia-1]] | |||
Revision as of 06:32, 9 April 2014
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1
Template:ABSTRACT PUBMED 24682828
Function
[TIA1_HUMAN] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
About this Structure
2mjn is a 1 chain structure. Full experimental information is available from OCA.
Reference
- Wang I, Hennig J, Jagtap PK, Sonntag M, Valcarcel J, Sattler M. Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1. Nucleic Acids Res. 2014 Mar 25. PMID:24682828 doi:https://dx.doi.org/10.1093/nar/gku193
