1a50: Difference between revisions
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{{STRUCTURE_1a50| PDB=1a50 | SCENE= }} | {{STRUCTURE_1a50| PDB=1a50 | SCENE= }} | ||
===CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUOROINDOLE PROPANOL PHOSPHATE=== | ===CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUOROINDOLE PROPANOL PHOSPHATE=== | ||
{{ABSTRACT_PUBMED_9548921}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TRPA_SALTY TRPA_SALTY]] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. [[http://www.uniprot.org/uniprot/TRPB_SALTY TRPB_SALTY]] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. | |||
The | |||
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:009548921</ref><references group="xtra"/> | <ref group="xtra">PMID:009548921</ref><references group="xtra"/><references/> | ||
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]] | [[Category: Salmonella enterica subsp. enterica serovar typhimurium]] | ||
[[Category: Tryptophan synthase]] | [[Category: Tryptophan synthase]] | ||
Revision as of 06:34, 10 April 2014
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUOROINDOLE PROPANOL PHOSPHATE
Template:ABSTRACT PUBMED 9548921
Function
[TRPA_SALTY] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. [TRPB_SALTY] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
About this Structure
1a50 is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar typhimurium. Full crystallographic information is available from OCA.
Reference
- Schneider TR, Gerhardt E, Lee M, Liang PH, Anderson KS, Schlichting I. Loop closure and intersubunit communication in tryptophan synthase. Biochemistry. 1998 Apr 21;37(16):5394-406. PMID:9548921 doi:https://dx.doi.org/10.1021/bi9728957
