1bfe: Difference between revisions
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{{STRUCTURE_1bfe| PDB=1bfe | SCENE= }} | {{STRUCTURE_1bfe| PDB=1bfe | SCENE= }} | ||
===THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95=== | ===THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95=== | ||
{{ABSTRACT_PUBMED_8674113}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DLG4_RAT DLG4_RAT]] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.<ref>PMID:15317815</ref> <ref>PMID:15358863</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:008674113</ref>< | <ref group="xtra">PMID:008674113</ref><references group="xtra"/><references/> | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Doyle, D A.]] | [[Category: Doyle, D A.]] | ||