1nw3: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_1nw3| PDB=1nw3 | SCENE= }} | {{STRUCTURE_1nw3| PDB=1nw3 | SCENE= }} | ||
===Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase=== | ===Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase=== | ||
{{ABSTRACT_PUBMED_12628190}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DOT1L_HUMAN DOT1L_HUMAN]] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. | |||
==About this Structure== | ==About this Structure== | ||
[[1nw3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[1nw3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NW3 OCA]. | ||
==See Also== | ==See Also== | ||
| Line 14: | Line 13: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:012628190</ref><references group="xtra"/> | <ref group="xtra">PMID:012628190</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Feng, Q.]] | [[Category: Feng, Q.]] | ||
[[Category: Li, Z H.]] | [[Category: Li, Z H.]] | ||
Revision as of 07:26, 16 April 2014
Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
Template:ABSTRACT PUBMED 12628190
Function
[DOT1L_HUMAN] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
About this Structure
1nw3 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA.
See Also
Reference
- Min J, Feng Q, Li Z, Zhang Y, Xu RM. Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase. Cell. 2003 Mar 7;112(5):711-23. PMID:12628190
