4o2b: Difference between revisions
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{{STRUCTURE_4o2b| PDB=4o2b | SCENE= }} | |||
===Tubulin-Colchicine complex=== | |||
{{ABSTRACT_PUBMED_24530796}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref> [[http://www.uniprot.org/uniprot/TBB2B_BOVIN TBB2B_BOVIN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). | |||
==About this Structure== | |||
[[4o2b]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat] and [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O2B OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024530796</ref><references group="xtra"/><references/> | |||
[[Category: Bos taurus]] | |||
[[Category: Buffalo rat]] | |||
[[Category: Chick]] | |||
[[Category: Bachmann, F.]] | |||
[[Category: Bargsten, K.]] | |||
[[Category: Buey, R M.]] | |||
[[Category: Franck, D.]] | |||
[[Category: Lane, H.]] | |||
[[Category: Pohlmann, J.]] | |||
[[Category: Prota, A E.]] | |||
[[Category: Reinelt, S.]] | |||
[[Category: Steinmetz, M O.]] | |||
[[Category: Alpha-tubulin]] | |||
[[Category: Beta-tubulin]] | |||
[[Category: Cell cycle]] | |||
[[Category: Cell cycle-inhibitor complex]] | |||
[[Category: Colchicine]] | |||
[[Category: Cytoskeleton]] | |||
[[Category: Gtpase]] | |||
[[Category: Ligase]] | |||
[[Category: Microtubule]] | |||
[[Category: Stathmin]] | |||
[[Category: Tubulin fold]] | |||