4msx: Difference between revisions

Revision as of 09:48, 16 April 2014

[SAD1_YEAST] Promotes the assembly of newly synthesized U4 snRNA into the U4/U6 snRNP particle. Required for splicing of pre-mRNA.^[1]

4msx is a 1 chain structure. Full crystallographic information is available from OCA.

Hadjivassiliou H, Rosenberg OS, Guthrie C. The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing. RNA. 2014 Mar 28. PMID:24681967 doi:https://dx.doi.org/10.1261/rna.042838.113

↑ Lygerou Z, Christophides G, Seraphin B. A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicing. Mol Cell Biol. 1999 Mar;19(3):2008-20. PMID:10022888

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-'''Unreleased structure'''
+{{STRUCTURE_4msx|  PDB=4msx  |  SCENE=  }}
+===Crystal structure of an essential yeast splicing factor===
+{{ABSTRACT_PUBMED_24681967}}
-The entry 4msx is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/SAD1_YEAST SAD1_YEAST]] Promotes the assembly of newly synthesized U4 snRNA into the U4/U6 snRNP particle. Required for splicing of pre-mRNA.<ref>PMID:10022888</ref>
-Authors: Hadjivassiliou, H., Guthrie, C., Rosenberg, O.S.
+==About this Structure==
+[[4msx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSX OCA].
-Description: Crystal structure of an essential yeast splicing factor
+==Reference==
+<ref group="xtra">PMID:024681967</ref><references group="xtra"/><references/>
+[[Category: Guthrie, C.]]
+[[Category: Hadjivassiliou, H.]]
+[[Category: Rosenberg, O S.]]
+[[Category: Deubiquitinase]]
+[[Category: Nuclear]]
+[[Category: Pre-mrna splicing]]
+[[Category: Pseudo-deubiquitinase]]
+[[Category: Spliceosome assembly]]
+[[Category: Splicing]]
+[[Category: Ubiquitin specific protease]]
+[[Category: Usp]]
+[[Category: Zinc finger ubiquitin binding protein]]
+[[Category: Znf-ubp]]