4o64: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Zinc fingers of KDM2B===

~~The entry 4o64 is ON HOLD~~ ~~until May 23 2015~~

==Function==

[[http://www.uniprot.org/uniprot/KDM2B_HUMAN KDM2B_HUMAN]] Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.<ref>PMID:16362057</ref> <ref>PMID:17994099</ref>

~~Authors~~: ~~Liu, K., Xu, C., Tempel, W., Walker, J.R., Arrowsmith,C.H., Bountra, C~~.~~, Edwards, A~~.M.~~, Min, J~~.~~, Structural Genomics Consortium (SGC)~~

==About this Structure==

[[4o64]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O64 OCA].

~~Description~~: ~~Zinc fingers of KDM2B~~

==Reference==

[[Category: Arrowsmith,C H.]]

[[Category: Bountra, C.]]

[[Category: Edwards, A M.]]

[[Category: Liu, K.]]

[[Category: Min, J.]]

[[Category: SGC, Structural Genomics Consortium.]]

[[Category: Tempel, W.]]

[[Category: Walker, J R.]]

[[Category: Xu, C.]]

[[Category: Cxxc zinc finger]]

[[Category: Metal binding protein]]

[[Category: Ring zinc finger]]

[[Category: Sgc]]

[[Category: Structural genomic]]

[[Category: Structural genomics consortium]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4o64|  PDB=4o64  |  SCENE=  }}
+===Zinc fingers of KDM2B===
-The entry 4o64 is ON HOLD  until May 23 2015
+==Function==
+[[http://www.uniprot.org/uniprot/KDM2B_HUMAN KDM2B_HUMAN]] Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.<ref>PMID:16362057</ref> <ref>PMID:17994099</ref>
-Authors: Liu, K., Xu, C., Tempel, W., Walker, J.R., Arrowsmith,C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
+==About this Structure==
+[[4o64]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O64 OCA].
-Description: Zinc fingers of KDM2B
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Arrowsmith,C H.]]
+[[Category: Bountra, C.]]
+[[Category: Edwards, A M.]]
+[[Category: Liu, K.]]
+[[Category: Min, J.]]
+[[Category: SGC, Structural Genomics Consortium.]]
+[[Category: Tempel, W.]]
+[[Category: Walker, J R.]]
+[[Category: Xu, C.]]
+[[Category: Cxxc zinc finger]]
+[[Category: Metal binding protein]]
+[[Category: Ring zinc finger]]
+[[Category: Sgc]]
+[[Category: Structural genomic]]
+[[Category: Structural genomics consortium]]