1ph7: Difference between revisions

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[[Image:1ph7.png|left|200px]]
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{{STRUCTURE_1ph7|  PDB=1ph7  |  SCENE=  }}  
{{STRUCTURE_1ph7|  PDB=1ph7  |  SCENE=  }}  
===CRYSTAL STRUCTURE OF THE OXYTRICHA NOVA TELOMERE END-BINDING PROTEIN COMPLEXED WITH NONCOGNATE SSDNA GGGGTTTTGIGG===
===CRYSTAL STRUCTURE OF THE OXYTRICHA NOVA TELOMERE END-BINDING PROTEIN COMPLEXED WITH NONCOGNATE SSDNA GGGGTTTTGIGG===
{{ABSTRACT_PUBMED_12912928}}


 
==Function==
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[[http://www.uniprot.org/uniprot/TEBB_OXYNO TEBB_OXYNO]] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification. [[http://www.uniprot.org/uniprot/TEBA_OXYNO TEBA_OXYNO]] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.
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{{ABSTRACT_PUBMED_12912928}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:012912928</ref><references group="xtra"/>
<ref group="xtra">PMID:012912928</ref><references group="xtra"/><references/>
[[Category: Sterkiella nova]]
[[Category: Sterkiella nova]]
[[Category: Schultz, S C.]]
[[Category: Schultz, S C.]]

Revision as of 10:43, 16 April 2014

Template:STRUCTURE 1ph7

CRYSTAL STRUCTURE OF THE OXYTRICHA NOVA TELOMERE END-BINDING PROTEIN COMPLEXED WITH NONCOGNATE SSDNA GGGGTTTTGIGG

Template:ABSTRACT PUBMED 12912928

Function

[TEBB_OXYNO] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification. [TEBA_OXYNO] May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication. Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.

About this Structure

1ph7 is a 5 chain structure with sequence from Sterkiella nova. Full crystallographic information is available from OCA.

Reference

  1. Theobald DL, Schultz SC. Nucleotide shuffling and ssDNA recognition in Oxytricha nova telomere end-binding protein complexes. EMBO J. 2003 Aug 15;22(16):4314-24. PMID:12912928 doi:https://dx.doi.org/10.1093/emboj/cdg415

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