1f7b: Difference between revisions

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{{Seed}}
[[Image:1f7b.png|left|200px]]
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{{STRUCTURE_1f7b|  PDB=1f7b  |  SCENE=  }}  
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===CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II IN COMPLEX WITH 4-OXO-SIALIC ACID===
===CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II IN COMPLEX WITH 4-OXO-SIALIC ACID===
{{ABSTRACT_PUBMED_11031117}}


 
==Function==
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[[http://www.uniprot.org/uniprot/NANA_HAEIN NANA_HAEIN]] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.
The line below this paragraph, {{ABSTRACT_PUBMED_11031117}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11031117 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11031117}}


==About this Structure==
==About this Structure==
1F7B is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F7B OCA].  
[[1f7b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F7B OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:11031117</ref><references group="xtra"/>
<ref group="xtra">PMID:011031117</ref><references group="xtra"/><references/>
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
[[Category: N-acetylneuraminate lyase]]
[[Category: N-acetylneuraminate lyase]]
Line 31: Line 18:
[[Category: Smith, B J.]]
[[Category: Smith, B J.]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
 
[[Category: Lyase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:48:59 2009''

Revision as of 10:47, 16 April 2014

Template:STRUCTURE 1f7b

CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II IN COMPLEX WITH 4-OXO-SIALIC ACID

Template:ABSTRACT PUBMED 11031117

Function

[NANA_HAEIN] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.

About this Structure

1f7b is a 2 chain structure with sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.

Reference

  1. Barbosa JA, Smith BJ, DeGori R, Ooi HC, Marcuccio SM, Campi EM, Jackson WR, Brossmer R, Sommer M, Lawrence MC. Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme. J Mol Biol. 2000 Oct 27;303(3):405-21. PMID:11031117 doi:https://dx.doi.org/10.1006/jmbi.2000.4138

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