1nu4: Difference between revisions
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m Protected "1nu4" [edit=sysop:move=sysop] |
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{{STRUCTURE_1nu4| PDB=1nu4 | SCENE= }} | {{STRUCTURE_1nu4| PDB=1nu4 | SCENE= }} | ||
===U1A RNA binding domain at 1.8 angstrom resolution reveals a pre-organized C-terminal helix=== | ===U1A RNA binding domain at 1.8 angstrom resolution reveals a pre-organized C-terminal helix=== | ||
{{ABSTRACT_PUBMED_12876372}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SNRPA_HUMAN SNRPA_HUMAN]] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5'-UGCAC-3' motif in vitro.<ref>PMID:9848648</ref> | |||
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:012876372</ref><references group="xtra"/> | <ref group="xtra">PMID:012876372</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Amare, A R.Ferre-D.]] | [[Category: Amare, A R.Ferre-D.]] | ||