4mrt: Difference between revisions
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{{STRUCTURE_4mrt| PDB=4mrt | SCENE= }} | |||
===Structure of the Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein=== | |||
{{ABSTRACT_PUBMED_24704508}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TYCC_BREPA TYCC_BREPA]] Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product. [[http://www.uniprot.org/uniprot/SFP_BACSU SFP_BACSU]] Activates the seven peptidyl carrier protein (PCP) domains of surfactin synthase SRF1/2/3 by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. Required for cells of B.subtilis to become producers of the lipopeptide antibiotics surfactin and plipastatin B1.<ref>PMID:8939709</ref> | |||
==About this Structure== | |||
[[4mrt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MRT OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024704508</ref><references group="xtra"/><references/> | |||
[[Category: Dikic, I.]] | |||
[[Category: Doetsch, V.]] | |||
[[Category: Guentert, P.]] | |||
[[Category: Henrich, E.]] | |||
[[Category: Kirchner, D K.]] | |||
[[Category: Koepke, J.]] | |||
[[Category: Kraas, F I.]] | |||
[[Category: Loehr, F.]] | |||
[[Category: Marahiel, M A.]] | |||
[[Category: Rahighi, S.]] | |||
[[Category: Tufar, P.]] | |||
[[Category: Pcp: aminoacyl/peptidyl carrier]] | |||
[[Category: Sfp: coenzyme a binding]] | |||
[[Category: Sfp: phosphopantetheine transferase]] | |||
[[Category: Transport protein-transferase complex]] | |||