2b8p: Difference between revisions

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Revision as of 08:20, 23 April 2014

Template:STRUCTURE 2b8p

Crystal structure of Acanthamoeba polyphaga mimivirus NDK, the first viral nucleoside diphosphate kinase

Template:ABSTRACT PUBMED 19439473

Function

[NDK_MIMIV] Plays a role in the synthesis of nucleoside triphosphates. This activity may optimize the replication of the AT-rich (73%) viral genome in a thymidine-limited host environment.

About this Structure

2b8p is a 2 chain structure with sequence from Mimivirus. Full crystallographic information is available from OCA.

Reference

  1. Jeudy S, Lartigue A, Claverie JM, Abergel C. Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase. J Virol. 2009 Jul;83(14):7142-50. Epub 2009 May 13. PMID:19439473 doi:10.1128/JVI.00511-09

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