2bfa: Difference between revisions
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{{STRUCTURE_2bfa| PDB=2bfa | SCENE= }} | {{STRUCTURE_2bfa| PDB=2bfa | SCENE= }} | ||
===LEISHMANIA MAJOR PTERIDINE REDUCTASE 1 IN COMPLEX WITH NADP AND CB3717=== | ===LEISHMANIA MAJOR PTERIDINE REDUCTASE 1 IN COMPLEX WITH NADP AND CB3717=== | ||
{{ABSTRACT_PUBMED_16055151}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PTR1_LEIMA PTR1_LEIMA]] Exhibits a NADPH-dependent biopterin reductase activity. Has good activity with folate and significant activity with dihydrofolate and dihydrobiopterin, but not with quinonoid dihydrobiopterin. Confers resistance to methotrexate (MTX).<ref>PMID:7972081</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[2bfa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BFA OCA]. | [[2bfa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BFA OCA]. | ||
==See Also== | |||
*[[Pteridine reductase|Pteridine reductase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:016055151</ref><references group="xtra"/> | <ref group="xtra">PMID:016055151</ref><references group="xtra"/><references/> | ||
[[Category: Leishmania major]] | [[Category: Leishmania major]] | ||
[[Category: Pteridine reductase]] | [[Category: Pteridine reductase]] | ||