1yde: Difference between revisions

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[[Image:1yde.png|left|200px]]
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{{STRUCTURE_1yde|  PDB=1yde  |  SCENE=  }}  
{{STRUCTURE_1yde|  PDB=1yde  |  SCENE=  }}  
===Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3===
===Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3===
{{ABSTRACT_PUBMED_17067289}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/DHR10_HUMAN DHR10_HUMAN]] Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).<ref>PMID:17067289</ref> 
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{{ABSTRACT_PUBMED_17067289}}


==About this Structure==
==About this Structure==
[[1yde]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YDE OCA].  
[[1yde]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YDE OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:017067289</ref><references group="xtra"/>
<ref group="xtra">PMID:017067289</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Arrowsmith, C.]]
[[Category: Arrowsmith, C.]]
[[Category: Bunkozci, G.]]
[[Category: Bunkozci, G.]]

Revision as of 08:21, 23 April 2014

Template:STRUCTURE 1yde

Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3

Template:ABSTRACT PUBMED 17067289

Function

[DHR10_HUMAN] Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).[1]

About this Structure

1yde is a 16 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  1. Lukacik P, Keller B, Bunkoczi G, Kavanagh KL, Lee WH, Adamski J, Oppermann U. Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. Biochem J. 2007 Mar 15;402(3):419-27. PMID:17067289 doi:BJ20061319
  1. ↑ Lukacik P, Keller B, Bunkoczi G, Kavanagh KL, Lee WH, Adamski J, Oppermann U. Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. Biochem J. 2007 Mar 15;402(3):419-27. PMID:17067289 doi:BJ20061319

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