2c91: Difference between revisions
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{{STRUCTURE_2c91| PDB=2c91 | SCENE= }} | {{STRUCTURE_2c91| PDB=2c91 | SCENE= }} | ||
===MOUSE SUCCINIC SEMIALDEHYDE REDUCTASE, AKR7A5=== | ===MOUSE SUCCINIC SEMIALDEHYDE REDUCTASE, AKR7A5=== | ||
{{ABSTRACT_PUBMED_16460003}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ARK72_MOUSE ARK72_MOUSE]] Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity).<ref>PMID:16460003</ref> | |||
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:016460003</ref>< | <ref group="xtra">PMID:016460003</ref><references group="xtra"/><references/> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Ellis, E M.]] | [[Category: Ellis, E M.]] | ||