1twq: Difference between revisions
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{{STRUCTURE_1twq| PDB=1twq | SCENE= }} | {{STRUCTURE_1twq| PDB=1twq | SCENE= }} | ||
===Crystal structure of the C-terminal PGN-binding domain of human PGRP-Ialpha in complex with PGN analog muramyl tripeptide=== | ===Crystal structure of the C-terminal PGN-binding domain of human PGRP-Ialpha in complex with PGN analog muramyl tripeptide=== | ||
{{ABSTRACT_PUBMED_15572450}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PGRP3_HUMAN PGRP3_HUMAN]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.<ref>PMID:16354652</ref> | |||
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:015572450</ref><references group="xtra"/> | <ref group="xtra">PMID:015572450</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Boons, G A.]] | [[Category: Boons, G A.]] | ||