Sandbox 123: Difference between revisions
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<scene name='36/365380/3zfz_1/8'>allosteric site</scene> (Tyr105, Asn146, Asp295, Tyr297), a conformational change occurs at the active site, opening it and allowing catalytic action to occur. | <scene name='36/365380/3zfz_1/8'>allosteric site</scene> (Tyr105, Asn146, Asp295, Tyr297), a conformational change occurs at the active site, opening it and allowing catalytic action to occur. | ||
The medicine, <scene name='36/365380/3zfz_1/12'>ceftaroline</scene>, mimics the substrate at the allosteric site opening the active site, allowing ceftaroline to enter and bind noncovalently. | The medicine, <scene name='36/365380/3zfz_1/12'>ceftaroline</scene>, mimics the substrate at the allosteric site opening the active site, allowing ceftaroline to <scene name='36/365380/3zfz_1/13'>enter and bind noncovalently</scene>. | ||