4kga: Difference between revisions

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'''Unreleased structure'''
==Crystal structure of kallikrein-related peptidase 4==
 
<StructureSection load='4kga' size='340' side='right' caption='[[4kga]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
The entry 4kga is ON HOLD  until Paper Publication
== Structural highlights ==
 
[[4kga]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KGA OCA]. <br>
Authors: Ilyichova, O.V., Swedberg, J.E., de Veer, S.J., Sit, K.C., Harris, J.M., Buckle, A.M.
<b>Related:</b> [[2bdg|2bdg]], [[2bdi|2bdi]], [[2bdh|2bdh]], [[4kel|4kel]], [[4k8y|4k8y]], [[4k1e|4k1e]]<br>
 
<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
Description: Crystal structure of kallikrein-related peptidase 4
== Disease ==
[[http://www.uniprot.org/uniprot/KLK4_HUMAN KLK4_HUMAN]] Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) [MIM:[http://omim.org/entry/204700 204700]]. AI2A1 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel.<ref>PMID:15235027</ref> 
== Function ==
[[http://www.uniprot.org/uniprot/KLK4_HUMAN KLK4_HUMAN]] Involved in enamel formation.<ref>PMID:15235027</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Buckle, A M.]]
[[Category: Harris, J M.]]
[[Category: Ilyichova, O V.]]
[[Category: Sit, K C.]]
[[Category: Swedberg, J E.]]
[[Category: Veer, S J.de.]]
[[Category: Hydrolase]]
[[Category: Kallikrein-4]]
[[Category: Klk4]]
[[Category: Protease]]
[[Category: Serine protease]]