Proton Channels: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Eric Martz (talk | contribs) mNo edit summary |
Eric Martz (talk | contribs) link to proton channel |
||
| Line 1: | Line 1: | ||
The M2 protein of influenza A virus is a proton channel. Its function is essential for productive infection by the virus. | The M2 protein of influenza A virus is a proton channel. Its function is essential for productive infection by the virus. | ||
See [[Category:Proton_channel]] for a list of all proton channel structures. | |||
In January, 2008, crystallographic and NMR structures were published side by side in ''Nature'' for the transmembrane domains of the M2 protein: [[3bkd]] and [[2rlf]]. The former appeared to be in an open conformation blocked by amantadine, while the latter appeared to be in a closed conformation stabilized by rimantadine. | In January, 2008, crystallographic and NMR structures were published side by side in ''Nature'' for the transmembrane domains of the M2 protein: [[3bkd]] and [[2rlf]]. The former appeared to be in an open conformation blocked by amantadine, while the latter appeared to be in a closed conformation stabilized by rimantadine. | ||
