1a0t: Difference between revisions
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[[Image:1a0t.gif|left|200px]] | [[Image:1a0t.gif|left|200px]] | ||
'''SUCROSE-SPECIFIC PORIN, WITH BOUND SUCROSE MOLECULES''' | {{Structure | ||
|PDB= 1a0t |SIZE=350|CAPTION= <scene name='initialview01'>1a0t</scene>, resolution 2.4Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=SUC:SUCROSE'>SUC</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene> | |||
|ACTIVITY= | |||
|GENE= SCRY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=602 Salmonella typhimurium]) | |||
}} | |||
'''SUCROSE-SPECIFIC PORIN, WITH BOUND SUCROSE MOLECULES''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1A0T is a [ | 1A0T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A0T OCA]. | ||
==Reference== | ==Reference== | ||
Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose., Forst D, Welte W, Wacker T, Diederichs K, Nat Struct Biol. 1998 Jan;5(1):37-46. PMID:[http:// | Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose., Forst D, Welte W, Wacker T, Diederichs K, Nat Struct Biol. 1998 Jan;5(1):37-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9437428 9437428] | ||
[[Category: Salmonella typhimurium]] | [[Category: Salmonella typhimurium]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: porin]] | [[Category: porin]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:51:16 2008'' | ||
Revision as of 07:51, 20 March 2008
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| 1a0t, resolution 2.4Å | |||||||||||||
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| Ligands: | SUC and CA | ||||||||||||
| Gene: | SCRY (Salmonella typhimurium) | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
SUCROSE-SPECIFIC PORIN, WITH BOUND SUCROSE MOLECULES
Overview
The X-ray structure of a sucrose-specific porin (ScrY) from Salmonella typhimurium has been determined by multiple isomorphous replacement at 2.4 A resolution both in its uncomplexed form and with bound sucrose. ScrY is a noncrystallographic trimer of identical subunits, each with 413 structurally well-defined amino acids. A monomer is built up of 18 anti-parallel beta-strands surrounding a hydrophilic pore, with a topology closely similar to that of maltoporin. Two non-overlapping sucrose-binding sites were identified in difference Fourier maps. The higher permeability for sucrose of ScrY as compared to maltoporin is mainly accounted for by differences in their pore-lining residues.
About this Structure
1A0T is a Single protein structure of sequence from Salmonella typhimurium. Full crystallographic information is available from OCA.
Reference
Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose., Forst D, Welte W, Wacker T, Diederichs K, Nat Struct Biol. 1998 Jan;5(1):37-46. PMID:9437428
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