Sandbox Reserved 930: Difference between revisions

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==Nucleotide binding pocket: ADP + Mg<sup>2+</sup>==
==Nucleotide binding pocket: ADP + Mg<sup>2+</sup>==


The nucleotide-binding pocket is located at the interface of the 50 kDa upper subdomain and the N-terminal subdomain <ref>PMID: 15184651</ref>, which is opposite to a deep cleft that bisects the actin-binding domain (Fig. 3).This part of protein involves an arrangement of a secondary structure mainly around the parallel 7-stranded <scene name='57/579700/Strands/1'> β-sheet</scene> (reference 1). Loops extending from b-strands interact with the adenine nucleotide.  
The nucleotide-binding pocket is located at the interface of the 50 kDa upper subdomain and the N-terminal subdomain <ref>PMID: 15184651</ref>, which is opposite to a deep cleft that bisects the actin-binding domain (Fig. 3).This part of protein involves an arrangement of a secondary structure mainly around the parallel 7-stranded <scene name='57/579700/Strands/1'> β-sheet</scene> (reference 1). Loops extending from the &beta;-strands interact with the adenine nucleotide.