1a2n: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
Line 1: Line 1:
[[Image:1a2n.jpg|left|200px]]<br /><applet load="1a2n" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1a2n.jpg|left|200px]]
caption="1a2n, resolution 2.8&Aring;" />
 
'''STRUCTURE OF THE C115A MUTANT OF MURA COMPLEXED WITH THE FLUORINATED ANALOG OF THE REACTION TETRAHEDRAL INTERMEDIATE'''<br />
{{Structure
|PDB= 1a2n |SIZE=350|CAPTION= <scene name='initialview01'>1a2n</scene>, resolution 2.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=TET:URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL-3-FLUORO-2-PHOSPHONOOXY)PROPIONIC ACID'>TET</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7]
|GENE=
}}
 
'''STRUCTURE OF THE C115A MUTANT OF MURA COMPLEXED WITH THE FLUORINATED ANALOG OF THE REACTION TETRAHEDRAL INTERMEDIATE'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
1A2N is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=TET:'>TET</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A2N OCA].  
1A2N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A2N OCA].  


==Reference==
==Reference==
Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant of MurA., Skarzynski T, Kim DH, Lees WJ, Walsh CT, Duncan K, Biochemistry. 1998 Feb 24;37(8):2572-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9485407 9485407]
Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant of MurA., Skarzynski T, Kim DH, Lees WJ, Walsh CT, Duncan K, Biochemistry. 1998 Feb 24;37(8):2572-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9485407 9485407]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 21: Line 30:
[[Category: udp-n-acetylglucosamine]]
[[Category: udp-n-acetylglucosamine]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:40:12 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:52:01 2008''
Retrieved from "https://proteopedia.org/1a2n"