1a5g: Difference between revisions

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[[Image:1a5g.gif|left|200px]]<br /><applet load="1a5g" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1a5g.gif|left|200px]]
caption="1a5g, resolution 2.06&Aring;" />
 
'''HUMAN THROMBIN COMPLEXED WITH NOVEL SYNTHETIC PEPTIDE MIMETIC INHIBITOR AND HIRUGEN'''<br />
{{Structure
|PDB= 1a5g |SIZE=350|CAPTION= <scene name='initialview01'>1a5g</scene>, resolution 2.06&Aring;
|SITE= <scene name='pdbsite=CAT:Active+Site'>CAT</scene>
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=BIC:3-AMINO-3-BENZYL-9-CARBOXAMIDE[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE'>BIC</scene> and <scene name='pdbligand=EOA:N-PHENETHYL-FORMAMIDE'>EOA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''HUMAN THROMBIN COMPLEXED WITH NOVEL SYNTHETIC PEPTIDE MIMETIC INHIBITOR AND HIRUGEN'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1A5G is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=BIC:'>BIC</scene> and <scene name='pdbligand=EOA:'>EOA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Known structural/functional Site: <scene name='pdbsite=CAT:Active+Site'>CAT</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A5G OCA].  
1A5G is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A5G OCA].  


==Reference==
==Reference==
Bound structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin., St Charles R, Matthews JH, Zhang E, Tulinsky A, J Med Chem. 1999 Apr 22;42(8):1376-83. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10212123 10212123]
Bound structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin., St Charles R, Matthews JH, Zhang E, Tulinsky A, J Med Chem. 1999 Apr 22;42(8):1376-83. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10212123 10212123]
[[Category: Hirudo medicinalis]]
[[Category: Hirudo medicinalis]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: complex (serine protease/inhibitor)]]
[[Category: complex (serine protease/inhibitor)]]


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