Sandbox Reserved 932: Difference between revisions
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Denmotoxin binds specifically to bird muscle nicotinic acetylcholine receptors preventing their normal function in signal transduction. This taxon specifity is reached by unique structural differences to other 3FTXs such as changes in the suggested binding loop of the protein. <ref name=Pawlak>Pawlak J. ''et al.'', [http://www.ncbi.nlm.nih.gov/pubmed/16864572 "Denmotoxin, a Three-finger Toxin from the Colubrid Snake Boiga dendrophila (Mangrove Catsnake) with Bird-specific Activity"], ''The Journal of Biological Chemistry: 281: 29030-29041'', September 29, 2006. Retrieved May 19, 2014.</ref> | Denmotoxin binds specifically to bird muscle nicotinic acetylcholine receptors preventing their normal function in signal transduction. This taxon specifity is reached by unique structural differences to other 3FTXs such as changes in the suggested binding loop of the protein. <ref name=Pawlak>Pawlak J. ''et al.'', [http://www.ncbi.nlm.nih.gov/pubmed/16864572 "Denmotoxin, a Three-finger Toxin from the Colubrid Snake Boiga dendrophila (Mangrove Catsnake) with Bird-specific Activity"], ''The Journal of Biological Chemistry: 281: 29030-29041'', September 29, 2006. Retrieved May 19, 2014.</ref> | ||
=Denmotoxin= | =Denmotoxin= | ||
<StructureSection load='2H5F' size='450' side='right' | <StructureSection load='2H5F' size='450' side='right' | ||
