1ai9: Difference between revisions

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[[Image:1ai9.gif|left|200px]]<br /><applet load="1ai9" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ai9.gif|left|200px]]
caption="1ai9, resolution 1.85&Aring;" />
 
'''CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE'''<br />
{{Structure
|PDB= 1ai9 |SIZE=350|CAPTION= <scene name='initialview01'>1ai9</scene>, resolution 1.85&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NDP:NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE'>NDP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3]
|GENE=
}}
 
'''CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1AI9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans] with <scene name='pdbligand=NDP:'>NDP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AI9 OCA].  
1AI9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AI9 OCA].  


==Reference==
==Reference==
X-ray crystallographic studies of Candida albicans dihydrofolate reductase. High resolution structures of the holoenzyme and an inhibited ternary complex., Whitlow M, Howard AJ, Stewart D, Hardman KD, Kuyper LF, Baccanari DP, Fling ME, Tansik RL, J Biol Chem. 1997 Nov 28;272(48):30289-98. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9374515 9374515]
X-ray crystallographic studies of Candida albicans dihydrofolate reductase. High resolution structures of the holoenzyme and an inhibited ternary complex., Whitlow M, Howard AJ, Stewart D, Hardman KD, Kuyper LF, Baccanari DP, Fling ME, Tansik RL, J Biol Chem. 1997 Nov 28;272(48):30289-98. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9374515 9374515]
[[Category: Candida albicans]]
[[Category: Candida albicans]]
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
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[[Category: reductase]]
[[Category: reductase]]


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